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Endogenous substances in biological samples

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Comparison of sample preparation strategies for the extraction of methylmalonic acid prior to LC-MS/MS analysis
A range of techniques of varying complexity were evaluated: protein precipitation, phospholipid depletion, supported liquid extraction and solid phase extraction using both silica and polymer-based mixed-mode anion exchange chemistries. Method performance was evaluated for evaporative effects, assay recovery, ion suppression and phospholipid removal.


Biotage ISOLUTE SLE+ applications
The ISOLUTE SLE+ applications e-book is designed to give an easy to use overview of the wide range of ISOLUTE SLE+ applications available.

Biotage Analytical Sample Preparation 2016
This catalog presents the extensive range of products for analytical sample preparation from Biotage. You may download the complete catalog, or the individual sections.


Norlab is now the direct contact for Biotage organic chemistry portfolio in Finland
A message from Daniel Herneson, Sales Director, Biotage.

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Norlab is now the direct contact for Biotage organic chemistry portfolio in Finland
A message from Daniel Herneson, Sales Director, Biotage.

Application notes
Extraction of methylmalonic acid from serum using ISOLUTE PPT+ protein precipitation plates prior to LC-MS/MS analysis
Date of creation: 
1 August 2017
Library code: 
11159
Extraction of methylmalonic acid from serum using ISOLUTE SLE+ prior to LC-MS/MS analysis
Date of creation: 
1 August 2017
Library code: 
11161
Extraction of methylmalonic acid from serum using ISOLUTE PLD+ prior to LC-MS/MS analysis
Date of creation: 
1 August 2017
Library code: 
11162
Extraction of methylmalonic acid from serum using ISOLUTE SAX prior to LC-MS/MS analysis
Date of creation: 
1 August 2017
Library code: 
11163
Extraction of methylmalonic acid from serum using EVOLUTE EXPRESS AX prior to LC-MS/MS analysis
Date of creation: 
1 August 2017
Library code: 
11164
Literature
Date of creation: 
30 December 2015
Library code: 
10563
Biotage ISOLUTE SLE+ Supported Liquid Extraction user guide
Date of creation: 
30 December 2015
Library code: 
10568