Study of temperature stability, fragmentation and aggregation of recombinant antibodies with asymmetrical flow FFF (AF4) and UV
Resource type:
Application note
Format:
pdf
Date of creation:
22 August 2018
Library code:
12184
In this study, Postnova investigated the influence of temperature on the stability, fragmentation and aggregation of recombinant antibodies. Thereby, they could clearly demonstrate the excellent applicability of AF4 coupled with UV as a monitoring tool for temperature-induced antibody decomposition revealing that the antibody itself is rather decomposed to fragments than to aggregates.
